Matthew Sikes is a human police officer and partner of George Francisco. Matthew Sikes is divorced and has a daughter.
Both, he and George are close Friends, even if he sometimes acts quite bemused about Tenctonese customs.When Matthew and George met for the first time, he refused to be the Partner of a "Slag", since his former partner, Sgt. William Tuggles, was killed during a gunfight with a Tenctonese Criminal. Later however, after he worked a while with George, he came to the conclusion that he was wrong about his prejudice towards Tenctonese and the two became very close friends.
He has an on-off relationship with Dr. Cathy Frankel, a newcomer bio-chemist which remains sketchy during the TV series. During the TV movies, their relationship blossoms and ends up with them taking 'sex' classes.